COVID 19-The Deadliest Pandemic of the Era

Corona virus disease 2019 (COVID-19) is caused by the SARS-CoV-2 (severe acute respiratory syndrome - coronavirus-2). It is one of the major pandemics of 21st century that killed more than 6.6 million people worldwide. The severity of COVID-19 symptoms can range from very mild, moderate to severe. However, an infected individual may have hardly one or two symptoms, and in some cases, there are no symptoms found in positive patients. The old population is at higher risk of serious illness from COVID-19, and the risk increases with age. People who have co-morbidity also may have a higher risk of serious illness. SARS-CoV-2 is spreading from human to human by close contact, via airborne droplets generated by coughing, talking, sneezing, kissing and smooching. Direct contact between a person or patient's body fluids, such as feces, and a surface, as well as indirect contact with fomites, infection also occurs if a patient touches at infected surface and then touches his nose, eyes, mouth. Looking towards the current situation of pandemic, it is suggested that the simple cares such as washing hands with soap, use of mask, social distancing, use of sanitizers and vaccination can prevent the subsequent spread of the virus. The current review, enlighten the statistics, genome organization, structure, pathogenicity, detection techniques, antiviral drug, available major vaccine and preventive measures for the management of the deadly disease. To defeat this universal enemy, we all require national as well as global solidarity, which makes hostage to the whole world.