EJMA. 2022; 2(2): 90-94 | DOI: 10.14744/ejma.2022.69875

How Should Immature Ovarian Teratoma with Gliomatosis Peritonei Be Treated? A Series of Three Rare Cases and Review of the Literature

Yusuf Ilhan¹, Hasan Şenol Coşkun, Hadice Elif Peştereli, Sema Sezgin Göksu, Elif Ocak Gedik, Havva Serap Toru, Ali Murat Tatlı
¹Department of Medical Oncology, Akdeniz University Faculty of Medicine, Antalya, Turkey
²Department of Pathology, Akdeniz University Faculty of Medicine, Antalya, Turkey

Immature ovarian teratoma (IT), also called malignant ovarian teratoma, is one of the ovarian germ cell tumors. Histologically, these neoplasms are typically differantiate towards the three germ cell layers. The metastatic implantation of mature glial tissue on the surface of the peritoneum, omentum, and abdominal lymph nodes is defined as gliomatosis peritonei (GP). It is an extremely rare disease and usually associated with ovarian teratomas, especially in IT. Because of its rarity, the prognostic effect of GP is unclear. Here, we presented three different patients who were diagnosed as IT with GP, and we also reviewed the literature to understand this disease better.

Keywords: Ovarian germ cell tumors, immature teratoma, gliomatosis peritonei, prognosis

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