Evaluation of Kidney Biopsies Performed in Patients Followed Up in the Nephrology Department of Our Hospital

Objectives: Renal biopsy plays a critical role in the diagnosis, prognosis and treatment management of renal parenchymal diseases. The aim of this study was to evaluate the clinicopathologic and laboratory characteristics of renal biopsies.
Methods: A total of 150 renal biopsies performed in the Nephrology Clinic of Bakırköy Dr. Sadi Konuk Training and Research Hospital between 2015 and 2017 were retrospectively evaluated. Biopsies of patients under 18 years of age, transplant kidney biopsies, biopsies without sufficient number of glomeruli for pathologic evaluation and biopsies evaluated in different pathology laboratories were excluded. Age, gender, laboratory data, indications for renal biopsy, histopathologic diagnosis and comorbidities of the patients were obtained from patient files and medical record system. These data were evaluated internally and comparatively.
Results: Among the patients who underwent renal biopsy, 44.67% were female and the male/female ratio was 1.23: 1. The mean age of the patients was 45.73±14.98 years (18-80 years). The most common indication for biopsy was nephrotic proteinuria (33.33%). The most common pathology in all age and gender groups was primary glomerulonephritis with 67.33%. The most common primary glomerular diseases were focal segmental glomerulosclerosis (FSGS) (41.58%), IgA nephropathy (24.75%) and membranous glomerulonephritis (MGN) (17.82%). The most common cause of secondary glomerulonephritis was amyloidosis (50%).
Conclusion: In this study, all indications for biopsy were evaluated. Our study presents results consistent with the local and national literature, but also reveals regional differences.