Seroprevalence of Cytomegalovirus Infection Among Pregnant Women with Prior Miscarriages in Dhaka, Bangladesh

Objectives: Compared to other infections, cytomegalovirus (CMV) infection is significantly more complicated during pregnancy since the virus frequently reactivates at this time, potentially increasing the risk of adverse pregnancy out-comes. Therefore, the purpose of this study was to assess the prevalence of human CMV infection among women who had a history of miscarriage.
Methods: The anti-CMV IgG was measured using the chemiluminescence method. A total of 300 pregnant women who had a number of previous miscarriages were tested. Women from a variety of socioeconomic backgrounds were taken into consideration.
Results: Among the study women, 246 women showed positive results, giving an 82% prevalence rate. Significantly higher prevalence rates (P<0.05) were observed with an increasing number of prior miscarriages. All of the study participants who had experienced three or more miscarriages were positive, compared to about 80% of participants with just two or fewer miscarriages.
Conclusion: It may be concluded that women with varying numbers of prior miscarriages had significantly different prevalences of anti-CMV IgG antibodies.