An Unusual Presentation of Growing Teratoma Syndrome

The growing teratoma syndroma (GTS) was first defined in 1982 as growth in masses despite the decrease of serum tumor markers after treatment with cytotoxic chemotherapy in non-seminamatous germ cell tumors. Due to the rarity of the GTS, tumor growth should not be mistaken for disease progression. Because this may cause oncological overtreatment in some patients. GTS is most common in the retroperitoneal region. However, it has been reported elsewhere (lung, lymph nodes, mediastinum, liver, and pineal gland). Since GTS is not responsive to chemotherapy and radiotherapy, the gold standart of treatment is the radical surgical excision of the mass. There are very few cases of GTS in the literature that develop from the supraclavicular lymph node. Here we present an unusual case of GTS at left supraclavicular and subcarinal lymph nodes.

Keywords: Growing teratoma syndrome, germ cell tumor, testis tumor.