Article
Open Access
Volume 4 · Issue 2 · 2024
pp. 96–101
Vitamin D Levels of Hospitalized Patients in Internal Medicine Clinic and Its Relationship with Clinical Parameters
Nurullah İlhan1, Süleyman Baş2, Funda Müşerref Türkmen3
1
Department of Medical Oncology, University of Health Sciences, Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, İstanbul, Türkiye
2
Department of Internal Medicine, University of Health Sciences, Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, İstanbul, Türkiye
3
Department of Internal Medicine, University of Health Sciences, Haydarpaşa Numune Training and Research Hospital, İstanbul, Türkiye
Abstract
Objectives: This study was conducted to determine the frequency of Vitamin D (VD) deficiency and to investigate whether there is a significant difference between sociodemographic and clinical characteristics of patients and 25-OH VD levels by examining 25-OH VD levels in patients 18 years and older admitted to our internal medicine clinic. Methods: This retrospective study was carried out in Haydarpaşa Numune Training and Research Hospital Internal Medicine clinic between May and June 2014, and the patients whose VD levels were measured were examined retrospectively through the hospital information system. Forty-nine patients with type 2 diabetes mellitus and 96 non-diabetic patients were included in the study. A control group of 51 healthy individuals was formed.
Results: A total of 145 patients and 51 healthy controls were included in the study. When the study group was classified according to the level of VD, severe deficiency in 76 cases, deficiency in 55 cases, failure in 14 cases were detected.We found that being over 75 years of age, female gender and malignancy predicted vitamin deficiency.When the VD levels of diabetic and non-diabetic patients were compared, VD levels of diabetic patients were found to be lower than non-diabetic patients, but not statistically significant.VD levels between diabetic, non diabetic female patients and healthy female volunteers were statistically different (p<0.001, p=0.001). When VD levels of diabetic and nondiabetic female patients were compared, no statistically significant difference was found (p=0.216).
Conclusion: VD deficiency and failure are common problems threatening healthy adults in our country, and VD levels are significantly lower in hospitalized patients. This seems to be related to many comorbid diseases. There is a need for more controlled work in this area.
Results: A total of 145 patients and 51 healthy controls were included in the study. When the study group was classified according to the level of VD, severe deficiency in 76 cases, deficiency in 55 cases, failure in 14 cases were detected.We found that being over 75 years of age, female gender and malignancy predicted vitamin deficiency.When the VD levels of diabetic and non-diabetic patients were compared, VD levels of diabetic patients were found to be lower than non-diabetic patients, but not statistically significant.VD levels between diabetic, non diabetic female patients and healthy female volunteers were statistically different (p<0.001, p=0.001). When VD levels of diabetic and nondiabetic female patients were compared, no statistically significant difference was found (p=0.216).
Conclusion: VD deficiency and failure are common problems threatening healthy adults in our country, and VD levels are significantly lower in hospitalized patients. This seems to be related to many comorbid diseases. There is a need for more controlled work in this area.
Keywords: Acute renal failure, autoimmune diseases, chronic renal failure, cirrhosis, coronary artery disease, diabetes mellitus, heart failure, hypertension, malignancy, sepsis, Vitamin D.
