Objectives: Intensive care units (ICUs) provide advanced monitoring and treatment for patients with life-threatening organ failure. This study aimed to evaluate the impact of vital signs and laboratory parameters on mortality in ICU patients.
Methods: A total of 498 patients were retrospectively analyzed. Patients aged ≥18 years who were hospitalized for at least 24 hours in the internal medicine ICU were included. Trauma patients, those admitted for surgical procedures, and postoperative patients were excluded. Demographic data, comorbidities, laboratory values, vital signs, nutritional status, respiratory support, and survival outcomes were obtained from electronic medical records.
Results: Of 498 patients, 266 (53.4%) died and 232 (46.6%) survived. Mortality was significantly associated with age, chronic renal disease, respiratory disease, impaired consciousness, APACHE score, and mechanical ventilation requirement. Deceased patients had higher levels of urea, creatinine, bilirubin, ALT, AST, CRP, MPV, lactate, and potassium, and lower levels of albumin, pH, HCO₃, sodium, and calcium (p<0.05).
Conclusion: Age, APACHE score, urea, albumin, eosinophil count, MPV, and lactate were identified as independent predictors of mortality in ICU patients.
Keywords: Intensive care unit, Mortality, Prognostic factors, Albumin