Article Open Access Volume 3 · Issue 1 · 2023 pp. 19–22

Seroprevalence of Cytomegalovirus Infection Among Pregnant Women with Prior Miscarriages in Dhaka, Bangladesh

Mohammad Ariful Islam1, Farzana Sharmin2, Mehedi Hasan1
1 Department of Microbiology, Jagannath University, Dhaka, Bangladesh
2 Department of Gynecology, Women and Children Hospital Uttara, NHN, Dhaka, Bangladesh
Published: 2023 DOI: 10.14744/ejma.2023.52296 Article ID: EJMA-52296
Abstract
Objectives: Compared to other infections, cytomegalovirus (CMV) infection is significantly more complicated during pregnancy since the virus frequently reactivates at this time, potentially increasing the risk of adverse pregnancy out-comes. Therefore, the purpose of this study was to assess the prevalence of human CMV infection among women who had a history of miscarriage.
Methods: The anti-CMV IgG was measured using the chemiluminescence method. A total of 300 pregnant women who had a number of previous miscarriages were tested. Women from a variety of socioeconomic backgrounds were taken into consideration.
Results: Among the study women, 246 women showed positive results, giving an 82% prevalence rate. Significantly higher prevalence rates (P<0.05) were observed with an increasing number of prior miscarriages. All of the study participants who had experienced three or more miscarriages were positive, compared to about 80% of participants with just two or fewer miscarriages.
Conclusion: It may be concluded that women with varying numbers of prior miscarriages had significantly different prevalences of anti-CMV IgG antibodies.

Keywords: anti-CMV IgG, Bangladesh, Cytomegalovirus, pregnant women, miscarriages

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