Notopterol for the Treatment of Human Disorders and Associated Secondary Complications: Concerns and Future Prospects

Notopterol is one of the main active phytochemical of Chinese herb Notopterygium incisum and Notopterygium franchetii. The aim of the present work is to collect all the scientific information of notopterol from different scientific databases and analyzed in the present work in order to know the health beneficial aspects of notopterol in medicine. Scientific data of notopterol has been collected in the present work from various scientific databases for its biological potential and pharmacological activities with its analytical aspects. However, detailed pharmacological activities of notopterol have also been discussed in the present paper. All the scientific data of notopterol have been collected from PubMed, Science Direct, Scopus, and Google in the present work. Presented scientific data of notopterol in this work signified the therapeutic effectiveness of notopterol in medicine. Scientific data analysis of the present work signified the biological importance of notopterol in medicine through its therapeutic effectiveness on acute myeloid leukemia, osteoporosis, Alzheimer's disease, pulmonary arterial hypertension and cytochrome P450. Further its antiproliferative, antiseizure, analgesic and pharmacokinetic parameters were also summarized in the present work through scientific data analysis of different scientific research work. Present work signified the biological importance of notopterol in medicine, which will be supportive to all the scientific peoples to explore the medicinal value of notopterol in medicine. However, more scientific investigation is needed in the area of pharmacokinetics and toxicology in order to know its biological significance in human and clinical uses.

Keywords: Antiproliferative, Antiseizure, Analgesic, Acute Myeloid Leukemia, Alzheimer's Disease, Coumarins, Cytochrome P450, Notopterol, Osteoporosis, Pulmonary Arterial Hypertension, Pharmacokinetic