The Relationship Between Frailty, Hematological Parameters, and Mortality in Older Adults with COVID-19

Objectives: Frailty is a geriatric syndrome characterized by a decrease in physical and physiological reserve and in-creased vulnerability and susceptibility to external stressors. In this study, we aimed to investigate the relationship between mortality, hematological parameters, and frailty in hospitalized older adults with COVID-19.
Methods: In this prospective study, 154 patients who were hospitalized between 01.11.2020 and 31.12.2020 at the Şişli Hamidiye Etfal Health Practice and Research Center COVID-19 inpatient clinics were included. Frailty was evaluated with the FRAIL scale. Complete blood count, CRP, ferritin, D-dimer, and troponin T levels were included as hematological pa-rameters.
Results: Forty-one of the 154 patients (26.6%) were categorized as frail. Troponin T levels were significantly higher in the frail patients compared with the non-frail patients (p<0.001). There was a statistically significant relationship between elevated troponin levels and mortality (1-month p=0.015, 3-month p=0.011).
Conclusion: In this study, there was no significant relationship between mortality and frailty status. A statistically sig-nificant relationship between elevated troponin levels and frailty was observed. There was also a significant relationship between elevated troponin levels and mortality in our study.
Keywords: COVID-19, frailty, laboratory, mortality

Keywords: COVID-19, frailty, laboratory, mortality